I am a lecturer in the Department of Biomedical Sciences of University of Health and Allied Sciences
EDUCATION
I received a Bachelor of Science degree in Biochemistry from Kwame Nkrumah University of Science and Technology in Ghana. I later pursued graduate studies in Biochemistry and Molecular Biology at University of Louisville in USA.
WORK EXPERIENCE
Following my undergraduate studies, I worked at the Department of Medical Biochemistry, University of Ghana for a year in fulfilment of my National Service duty. I later gained employment at University of Cape Coast School of Medical Sciences as a Research Assistant. A position I held for two years before pursing further studies.
RESEARCH OUTPUT
My graduate work focused on understanding the therapeutic potential of carnosine, a dipeptide, in critical limb ischemia. Using rodent models we examined the effect of carnosine on recovery from hindlimb ischemia and identified arterial remodeling and increased capillary density to be partly responsible for improved revascularization in treated mice. The effect of exercise and factors such as regulation of enzymes in carnosine metabolism on muscle carnosine content was also investigated.
During these studies I developed a keen interest in understanding the role of innate immunity in vascular disease pathogenesis. Using animal models and human samples I seek to understand how activation of the immune system by infectious agents could affect the cardiovascular system and identify possible mechanistic pathways that are involved.